Contraindicated (one)nirmatrelvir/ritonavir will improve the level or outcome of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism.rufinamide will reduce the level or influence of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.If you skip a dose, acquire it once you may. If it is almost time